Comparative clinical efficacy of propolis mouthrinse in the management patients with chronic generalized gingivitis: a randomized clinical trial
Abstract
Aim: The aim of the present study was to evaluate the clinical efficacy of propolis and chlorhexidine digluconate containing mouthrinse on a plaque accumulation and gingival inflammation in 14-day period in patients with generalized chronic gingivitis.
Materials & Methods: Thirty subjects were randomly divided into three groups of ten subjects each, which received a propolis-containing mouthrinse, or Saline (a negative control) or Chlorhexidine (a positive control). Plaque and gingival indexes were recorded at baseline and at the end of the 14th days.
Results: Chlorhexidine was the most effective in reducing gingival index compared to the other groups and no significant differences were observed between propolis and saline groups (P<0.05). There were no significant differences among groups for plaque index at the end of the 14th days (P>0.05).
Conclusion: Propolis mouthrinse is promising agent as an alternative to other antimicrobial agents in the mechanical plaque control and gingivitis treatment, but further randomized controlled trials are needed with increased number of individuals.
Clinical Significance: Mechanical plaque control mechanism plays an essential role in reducing microbial burden among patients with gingivitis. However, microorganisms present at many areas of the oral cavity are not mechanically reachable. Therefore, a chemical mechanism; in conjunction with mechanical procedures can play an important role the management of gingival diseases.
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